Economic activity is dispersed throughout the state. Economic Share measures the percentage of the state's economy that is accounted for by an individual county. The economic share is measured as the average of the percentage of the state's employment, population, and personal income that occurs in a particular county.
The table below presents those counties that account for a large proportion of the state's economy, based on employment, population, and income. Missouri's metropolitan areas account for a major part of the state's economy with St. Louis County (19.16%) and Jackson County (11.67%) together tallying nearly one-third of the total. Conversely, several counties in the state account for less than 0.1% of the state's economy.
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From 2000 to 2010, county contribution to the state's economy has not changed drastically. However, there have been some shifts in Missouri's economic composition. The map below shows the change in county share from 2000 to 2010. Counties shaded orange and darker lost economic share over the period, while counties shaded yellow and lighter had increasing shares.
The most notable shift is found in the St. Louis and Kansas City areas as St. Louis County, St. Louis City, and Jackson County decreased in share while surrounding counties generally increased, particularly St. Charles County. Clay County in the Kansas City area and Christian County in southwest Missouri area also gained significantly in economic share.

| 2010 Economic Share Factors | ||||||
| Area | 2009 Personal Income (000s) | 2009 Personal Income Share | 2010 Population | 2010 Population Share | 2010 Employment | 2010 Employment Share |
| Missouri | 216,637,311 | 100.0% | 6,011,741 | 100.0% | 2,725,529 | 100.0% |
| Adair | 681,427 | 0.3% | 25,129 | 0.4% | 11,969 | 0.4% |
| Andrew | 697,606 | 0.3% | 17,367 | 0.3% | 9,149 | 0.3% |
| Atchison | 231,016 | 0.1% | 5,894 | 0.1% | 2,854 | 0.1% |
| Audrain | 776,038 | 0.4% | 25,232 | 0.4% | 10,732 | 0.4% |
| Barry | 986,575 | 0.5% | 35,911 | 0.6% | 15,302 | 0.6% |
| Barton | 349,194 | 0.2% | 12,289 | 0.2% | 4,536 | 0.2% |
| Bates | 547,353 | 0.3% | 16,717 | 0.3% | 6,626 | 0.2% |
| Benton | 512,582 | 0.2% | 18,399 | 0.3% | 7,222 | 0.3% |
| Bollinger | 333,408 | 0.2% | 11,732 | 0.2% | 4,953 | 0.2% |
| Boone | 5,731,093 | 2.6% | 158,682 | 2.6% | 83,396 | 3.1% |
| Buchanan | 2,834,249 | 1.3% | 89,811 | 1.5% | 44,261 | 1.6% |
| Butler | 1,386,940 | 0.6% | 41,504 | 0.7% | 19,039 | 0.7% |
| Caldwell | 311,222 | 0.1% | 9,227 | 0.2% | 3,692 | 0.1% |
| Callaway | 1,226,443 | 0.6% | 44,149 | 0.7% | 20,911 | 0.8% |
| Camden | 1,341,074 | 0.6% | 40,419 | 0.7% | 18,004 | 0.7% |
| Cape Girardeau | 2,535,422 | 1.2% | 74,781 | 1.2% | 35,432 | 1.3% |
| Carroll | 321,537 | 0.1% | 9,598 | 0.2% | 4,315 | 0.2% |
| Carter | 157,216 | 0.1% | 6,059 | 0.1% | 2,811 | 0.1% |
| Cass | 3,390,257 | 1.6% | 101,153 | 1.7% | 44,512 | 1.6% |
| Cedar | 347,849 | 0.2% | 13,417 | 0.2% | 6,016 | 0.2% |
| Chariton | 267,350 | 0.1% | 7,642 | 0.1% | 3,885 | 0.1% |
| Christian | 2,166,549 | 1.0% | 79,065 | 1.3% | 37,188 | 1.4% |
| Clark | 214,641 | 0.1% | 7,132 | 0.1% | 3,119 | 0.1% |
| Clay | 8,195,041 | 3.8% | 230,639 | 3.8% | 108,551 | 4.0% |
| Clinton | 715,727 | 0.3% | 21,086 | 0.4% | 8,967 | 0.3% |
| Cole | 2,969,047 | 1.4% | 75,943 | 1.3% | 37,520 | 1.4% |
| Cooper | 510,730 | 0.2% | 17,493 | 0.3% | 7,866 | 0.3% |
| Crawford | 677,930 | 0.3% | 23,671 | 0.4% | 10,452 | 0.4% |
| Dade | 205,423 | 0.1% | 7,306 | 0.1% | 3,173 | 0.1% |
| Dallas | 432,214 | 0.2% | 16,649 | 0.3% | 6,442 | 0.2% |
| Daviess | 219,498 | 0.1% | 8,080 | 0.1% | 3,408 | 0.1% |
| DeKalb | 280,135 | 0.1% | 12,238 | 0.2% | 4,560 | 0.2% |
| Dent | 407,265 | 0.2% | 15,174 | 0.3% | 6,191 | 0.2% |
| Douglas | 322,577 | 0.1% | 13,373 | 0.2% | 5,510 | 0.2% |
| Dunklin | 917,068 | 0.4% | 31,035 | 0.5% | 12,751 | 0.5% |
| Franklin | 3,492,283 | 1.6% | 101,308 | 1.7% | 46,868 | 1.7% |
| Gasconade | 464,824 | 0.2% | 15,178 | 0.3% | 6,701 | 0.2% |
| Gentry | 219,804 | 0.1% | 6,030 | 0.1% | 3,308 | 0.1% |
| Greene | 9,353,747 | 4.3% | 269,500 | 4.5% | 127,533 | 4.7% |
| Grundy | 300,032 | 0.1% | 10,255 | 0.2% | 4,418 | 0.2% |
| Harrison | 246,315 | 0.1% | 8,684 | 0.1% | 3,952 | 0.1% |
| Henry | 697,650 | 0.3% | 22,178 | 0.4% | 9,554 | 0.4% |
| Hickory | 207,525 | 0.1% | 8,867 | 0.1% | 3,069 | 0.1% |
| Holt | 180,710 | 0.1% | 4,867 | 0.1% | 2,495 | 0.1% |
| Howard | 347,812 | 0.2% | 9,784 | 0.2% | 4,729 | 0.2% |
| Howell | 1,036,214 | 0.5% | 39,428 | 0.7% | 17,666 | 0.6% |
| Iron | 314,189 | 0.1% | 9,741 | 0.2% | 4,374 | 0.2% |
| Jackson | 26,152,339 | 12.1% | 710,455 | 11.8% | 303,464 | 11.1% |
| Jasper | 3,387,673 | 1.6% | 119,704 | 2.0% | 53,042 | 1.9% |
| Jefferson | 7,144,689 | 3.3% | 220,066 | 3.7% | 104,134 | 3.8% |
| Johnson | 1,447,445 | 0.7% | 52,703 | 0.9% | 23,242 | 0.9% |
| Knox | 124,388 | 0.1% | 3,980 | 0.1% | 2,103 | 0.1% |
| Laclede | 920,293 | 0.4% | 35,626 | 0.6% | 14,330 | 0.5% |
| Lafayette | 1,200,290 | 0.6% | 32,724 | 0.5% | 14,072 | 0.5% |
| Lawrence | 970,360 | 0.4% | 37,648 | 0.6% | 17,084 | 0.6% |
| Lewis | 280,935 | 0.1% | 9,805 | 0.2% | 4,965 | 0.2% |
| Lincoln | 1,462,936 | 0.7% | 53,781 | 0.9% | 24,018 | 0.9% |
| Linn | 382,589 | 0.2% | 12,606 | 0.2% | 5,353 | 0.2% |
| Livingston | 475,998 | 0.2% | 14,198 | 0.2% | 6,438 | 0.2% |
| McDonald | 569,576 | 0.3% | 23,070 | 0.4% | 9,845 | 0.4% |
| Macon | 463,926 | 0.2% | 15,489 | 0.3% | 7,354 | 0.3% |
| Madison | 311,160 | 0.1% | 12,233 | 0.2% | 5,573 | 0.2% |
| Maries | 244,397 | 0.1% | 8,875 | 0.1% | 4,462 | 0.2% |
| Marion | 892,545 | 0.4% | 28,457 | 0.5% | 13,536 | 0.5% |
| Mercer | 100,194 | 0.0% | 3,436 | 0.1% | 1,695 | 0.1% |
| Miller | 641,270 | 0.3% | 24,647 | 0.4% | 10,678 | 0.4% |
| Mississippi | 376,082 | 0.2% | 13,353 | 0.2% | 5,420 | 0.2% |
| Moniteau | 464,555 | 0.2% | 15,218 | 0.3% | 6,808 | 0.2% |
| Monroe | 269,173 | 0.1% | 8,738 | 0.1% | 3,382 | 0.1% |
| Montgomery | 370,652 | 0.2% | 11,755 | 0.2% | 5,299 | 0.2% |
| Morgan | 592,611 | 0.3% | 20,526 | 0.3% | 7,769 | 0.3% |
| New Madrid | 524,493 | 0.2% | 17,353 | 0.3% | 7,751 | 0.3% |
| Newton | 1,812,703 | 0.8% | 56,154 | 0.9% | 25,449 | 0.9% |
| Nodaway | 609,332 | 0.3% | 22,222 | 0.4% | 11,171 | 0.4% |
| Oregon | 250,784 | 0.1% | 10,450 | 0.2% | 4,133 | 0.2% |
| Osage | 454,671 | 0.2% | 13,429 | 0.2% | 6,795 | 0.2% |
| Ozark | 218,710 | 0.1% | 9,316 | 0.2% | 3,944 | 0.1% |
| Pemiscot | 564,160 | 0.3% | 18,104 | 0.3% | 7,430 | 0.3% |
| Perry | 552,199 | 0.3% | 18,649 | 0.3% | 9,831 | 0.4% |
| Pettis | 1,247,813 | 0.6% | 41,775 | 0.7% | 18,268 | 0.7% |
| Phelps | 1,325,992 | 0.6% | 42,810 | 0.7% | 20,076 | 0.7% |
| Pike | 505,181 | 0.2% | 18,448 | 0.3% | 8,176 | 0.3% |
| Platte | 3,832,983 | 1.8% | 92,016 | 1.5% | 45,217 | 1.7% |
| Polk | 795,600 | 0.4% | 30,551 | 0.5% | 12,724 | 0.5% |
| Pulaski | 1,969,400 | 0.9% | 46,637 | 0.8% | 19,222 | 0.7% |
| Putnam | 126,115 | 0.1% | 4,744 | 0.1% | 2,209 | 0.1% |
| Ralls | 310,642 | 0.1% | 9,594 | 0.2% | 5,111 | 0.2% |
| Randolph | 721,528 | 0.3% | 25,542 | 0.4% | 11,400 | 0.4% |
| Ray | 805,264 | 0.4% | 23,284 | 0.4% | 9,783 | 0.4% |
| Reynolds | 175,823 | 0.1% | 6,236 | 0.1% | 2,182 | 0.1% |
| Ripley | 343,277 | 0.2% | 13,416 | 0.2% | 5,960 | 0.2% |
| St. Charles | 13,679,566 | 6.3% | 358,667 | 6.0% | 178,111 | 6.5% |
| St. Clair | 243,697 | 0.1% | 9,336 | 0.2% | 3,599 | 0.1% |
| Ste. Genevieve | 580,285 | 0.3% | 17,601 | 0.3% | 8,852 | 0.3% |
| St. Francois | 1,723,237 | 0.8% | 64,273 | 1.1% | 26,310 | 1.0% |
| St. Louis | 51,817,478 | 23.9% | 991,974 | 16.5% | 465,389 | 17.1% |
| St. Louis City | 11,419,877 | 5.3% | 356,009 | 5.9% | 138,966 | 5.1% |
| Saline | 796,858 | 0.4% | 23,012 | 0.4% | 10,377 | 0.4% |
| Schuyler | 105,425 | 0.0% | 4,124 | 0.1% | 1,882 | 0.1% |
| Scotland | 132,597 | 0.1% | 4,802 | 0.1% | 2,211 | 0.1% |
| Scott | 1,299,291 | 0.6% | 41,124 | 0.7% | 17,769 | 0.7% |
| Shannon | 183,540 | 0.1% | 8,334 | 0.1% | 2,806 | 0.1% |
| Shelby | 204,225 | 0.1% | 6,313 | 0.1% | 2,897 | 0.1% |
| Stoddard | 894,808 | 0.4% | 29,253 | 0.5% | 13,608 | 0.5% |
| Stone | 973,867 | 0.4% | 31,290 | 0.5% | 13,604 | 0.5% |
| Sullivan | 218,910 | 0.1% | 6,820 | 0.1% | 3,333 | 0.1% |
| Taney | 1,382,582 | 0.6% | 48,900 | 0.8% | 23,899 | 0.9% |
| Texas | 578,865 | 0.3% | 24,650 | 0.4% | 10,079 | 0.4% |
| Vernon | 579,775 | 0.3% | 20,253 | 0.3% | 8,822 | 0.3% |
| Warren | 1,023,168 | 0.5% | 31,604 | 0.5% | 14,738 | 0.5% |
| Washington | 602,420 | 0.3% | 24,492 | 0.4% | 8,599 | 0.3% |
| Wayne | 331,884 | 0.2% | 12,333 | 0.2% | 5,442 | 0.2% |
| Webster | 934,554 | 0.4% | 36,977 | 0.6% | 15,135 | 0.6% |
| Worth | 59,520 | 0.0% | 1,952 | 0.0% | 1,045 | 0.0% |
| Wright | 417,335 | 0.2% | 18,009 | 0.3% | 7,176 | 0.3% |