See 2008 County Population Estimates map.
See 2000-2008 County Percent Change in Population Estimates map.
| 2008 Population Estimates | |||||||
| County | 2000 | July 1, 2007 | July 1, 2008 | %Chg 2000 to 2008 | Chg 2000 to 2008 | %Chg 2007 to 2008 | Chg 2007 to 2008 |
| Missouri | 5,595,211 | 5,878,399 | 5,911,605 | 5.7% | 316,394 | 0.6% | 33,206 |
| Adair County | 24,977 | 24,616 | 24,943 | -0.1% | -34 | 1.3% | 327 |
| Andrew County | 16,492 | 16,833 | 16,923 | 2.6% | 431 | 0.5% | 90 |
| Atchison County | 6,430 | 6,099 | 6,031 | -6.2% | -399 | -1.1% | -68 |
| Audrain County | 25,853 | 25,829 | 26,049 | 0.8% | 196 | 0.9% | 220 |
| Barry County | 34,010 | 36,103 | 36,301 | 6.7% | 2,291 | 0.5% | 198 |
| Barton County | 12,541 | 12,717 | 12,531 | -0.1% | -10 | -1.5% | -186 |
| Bates County | 16,653 | 17,002 | 17,075 | 2.5% | 422 | 0.4% | 73 |
| Benton County | 17,180 | 18,437 | 18,349 | 6.8% | 1,169 | -0.5% | -88 |
| Bollinger County | 12,029 | 12,114 | 11,990 | -0.3% | -39 | -1.0% | -124 |
| Boone County | 135,454 | 152,049 | 154,365 | 14.0% | 18,911 | 1.5% | 2,316 |
| Buchanan County | 85,998 | 89,013 | 89,408 | 4.0% | 3,410 | 0.4% | 395 |
| Butler County | 40,867 | 41,230 | 41,383 | 1.3% | 516 | 0.4% | 153 |
| Caldwell County | 8,969 | 9,273 | 9,248 | 3.1% | 279 | -0.3% | -25 |
| Callaway County | 40,766 | 43,180 | 43,464 | 6.6% | 2,698 | 0.7% | 284 |
| Camden County | 37,051 | 40,407 | 40,664 | 9.8% | 3,613 | 0.6% | 257 |
| Cape Girardeau County | 68,693 | 72,642 | 73,243 | 6.6% | 4,550 | 0.8% | 601 |
| Carroll County | 10,285 | 9,855 | 9,756 | -5.1% | -529 | -1.0% | -99 |
| Carter County | 5,941 | 5,913 | 5,890 | -0.9% | -51 | -0.4% | -23 |
| Cass County | 82,092 | 96,927 | 98,429 | 19.9% | 16,337 | 1.5% | 1,502 |
| Cedar County | 13,733 | 13,707 | 13,652 | -0.6% | -81 | -0.4% | -55 |
| Chariton County | 8,438 | 7,822 | 7,740 | -8.3% | -698 | -1.0% | -82 |
| Christian County | 54,285 | 72,954 | 75,479 | 39.0% | 21,194 | 3.5% | 2,525 |
| Clark County | 7,416 | 7,212 | 7,180 | -3.2% | -236 | -0.4% | -32 |
| Clay County | 184,006 | 211,525 | 215,707 | 17.2% | 31,701 | 2.0% | 4,182 |
| Clinton County | 18,979 | 20,975 | 21,094 | 11.1% | 2,115 | 0.6% | 119 |
| Cole County | 71,397 | 73,506 | 74,313 | 4.1% | 2,916 | 1.1% | 807 |
| Cooper County | 16,670 | 17,555 | 17,535 | 5.2% | 865 | -0.1% | -20 |
| Crawford County | 22,804 | 24,027 | 23,970 | 5.1% | 1,166 | -0.2% | -57 |
| Dade County | 7,923 | 7,495 | 7,418 | -6.4% | -505 | -1.0% | -77 |
| Dallas County | 15,661 | 16,815 | 16,844 | 7.6% | 1,183 | 0.2% | 29 |
| Daviess County | 8,016 | 7,957 | 7,911 | -1.3% | -105 | -0.6% | -46 |
| DeKalb County | 11,597 | 12,218 | 12,275 | 5.8% | 678 | 0.5% | 57 |
| Dent County | 14,927 | 15,029 | 15,199 | 1.8% | 272 | 1.1% | 170 |
| Douglas County | 13,084 | 13,348 | 13,438 | 2.7% | 354 | 0.7% | 90 |
| Dunklin County | 33,155 | 31,609 | 31,454 | -5.1% | -1,701 | -0.5% | -155 |
| Franklin County | 93,807 | 99,922 | 100,898 | 7.6% | 7,091 | 1.0% | 976 |
| Gasconade County | 15,342 | 15,366 | 15,261 | -0.5% | -81 | -0.7% | -105 |
| Gentry County | 6,861 | 6,226 | 6,185 | -9.9% | -676 | -0.7% | -41 |
| Greene County | 240,391 | 263,793 | 266,944 | 11.0% | 26,553 | 1.2% | 3,151 |
| Grundy County | 10,432 | 10,095 | 10,125 | -2.9% | -307 | 0.3% | 30 |
| Harrison County | 8,850 | 8,846 | 8,844 | -0.1% | -6 | 0.0% | -2 |
| Henry County | 21,997 | 22,347 | 22,179 | 0.8% | 182 | -0.8% | -168 |
| Hickory County | 8,940 | 9,108 | 9,048 | 1.2% | 108 | -0.7% | -60 |
| Holt County | 5,351 | 4,962 | 4,905 | -8.3% | -446 | -1.1% | -57 |
| Howard County | 10,212 | 9,867 | 9,918 | -2.9% | -294 | 0.5% | 51 |
| Howell County | 37,238 | 38,604 | 39,000 | 4.7% | 1,762 | 1.0% | 396 |
| Iron County | 10,697 | 10,002 | 9,918 | -7.3% | -779 | -0.8% | -84 |
| Jackson County | 654,880 | 666,000 | 668,417 | 2.1% | 13,537 | 0.4% | 2,417 |
| Jasper County | 104,686 | 115,049 | 116,813 | 11.6% | 12,127 | 1.5% | 1,764 |
| Jefferson County | 198,099 | 215,764 | 217,679 | 9.9% | 19,580 | 0.9% | 1,915 |
| Johnson County | 48,258 | 51,898 | 52,016 | 7.8% | 3,758 | 0.2% | 118 |
| Knox County | 4,361 | 4,045 | 4,020 | -7.8% | -341 | -0.6% | -25 |
| Laclede County | 32,513 | 35,346 | 35,524 | 9.3% | 3,011 | 0.5% | 178 |
| Lafayette County | 32,960 | 32,667 | 32,913 | -0.1% | -47 | 0.8% | 246 |
| Lawrence County | 35,204 | 37,629 | 37,757 | 7.3% | 2,553 | 0.3% | 128 |
| Lewis County | 10,494 | 10,031 | 9,951 | -5.2% | -543 | -0.8% | -80 |
| Lincoln County | 38,944 | 51,432 | 52,775 | 35.5% | 13,831 | 2.6% | 1,343 |
| Linn County | 13,754 | 12,684 | 12,580 | -8.5% | -1,174 | -0.8% | -104 |
| Livingston County | 14,558 | 14,181 | 14,213 | -2.4% | -345 | 0.2% | 32 |
| McDonald County | 21,681 | 22,803 | 22,731 | 4.8% | 1,050 | -0.3% | -72 |
| Macon County | 15,762 | 15,559 | 15,621 | -0.9% | -141 | 0.4% | 62 |
| Madison County | 11,800 | 12,170 | 12,276 | 4.0% | 476 | 0.9% | 106 |
| Maries County | 8,903 | 9,110 | 9,046 | 1.6% | 143 | -0.7% | -64 |
| Marion County | 28,289 | 28,157 | 28,225 | -0.2% | -64 | 0.2% | 68 |
| Mercer County | 3,757 | 3,496 | 3,523 | -6.2% | -234 | 0.8% | 27 |
| Miller County | 23,564 | 24,867 | 24,949 | 5.9% | 1,385 | 0.3% | 82 |
| Mississippi County | 13,427 | 13,589 | 13,504 | 0.6% | 77 | -0.6% | -85 |
| Moniteau County | 14,827 | 15,126 | 15,121 | 2.0% | 294 | 0.0% | -5 |
| Monroe County | 9,311 | 9,167 | 9,127 | -2.0% | -184 | -0.4% | -40 |
| Montgomery County | 12,136 | 11,888 | 11,804 | -2.7% | -332 | -0.7% | -84 |
| Morgan County | 19,309 | 20,794 | 20,861 | 8.0% | 1,552 | 0.3% | 67 |
| New Madrid County | 19,760 | 17,757 | 17,589 | -11.0% | -2,171 | -0.9% | -168 |
| Newton County | 52,636 | 55,994 | 56,120 | 6.6% | 3,484 | 0.2% | 126 |
| Nodaway County | 21,912 | 22,059 | 22,054 | 0.6% | 142 | 0.0% | -5 |
| Oregon County | 10,344 | 10,285 | 10,264 | -0.8% | -80 | -0.2% | -21 |
| Osage County | 13,062 | 13,358 | 13,465 | 3.1% | 403 | 0.8% | 107 |
| Ozark County | 9,542 | 9,217 | 9,227 | -3.3% | -315 | 0.1% | 10 |
| Pemiscot County | 20,047 | 18,740 | 18,515 | -7.6% | -1,532 | -1.2% | -225 |
| Perry County | 18,132 | 18,741 | 18,743 | 3.4% | 611 | 0.0% | 2 |
| Pettis County | 39,403 | 40,748 | 41,006 | 4.1% | 1,603 | 0.6% | 258 |
| Phelps County | 39,825 | 42,443 | 42,205 | 6.0% | 2,380 | -0.6% | -238 |
| Pike County | 18,351 | 18,430 | 18,476 | 0.7% | 125 | 0.2% | 46 |
| Platte County | 73,781 | 84,722 | 85,896 | 16.4% | 12,115 | 1.4% | 1,174 |
| Polk County | 26,992 | 30,162 | 30,404 | 12.6% | 3,412 | 0.8% | 242 |
| Pulaski County | 41,165 | 44,300 | 44,546 | 8.2% | 3,381 | 0.6% | 246 |
| Putnam County | 5,223 | 4,892 | 4,862 | -6.9% | -361 | -0.6% | -30 |
| Ralls County | 9,626 | 9,846 | 9,832 | 2.1% | 206 | -0.1% | -14 |
| Randolph County | 24,663 | 25,635 | 25,723 | 4.3% | 1,060 | 0.3% | 88 |
| Ray County | 23,354 | 23,446 | 23,445 | 0.4% | 91 | 0.0% | -1 |
| Reynolds County | 6,689 | 6,426 | 6,388 | -4.5% | -301 | -0.6% | -38 |
| Ripley County | 13,509 | 13,524 | 13,485 | -0.2% | -24 | -0.3% | -39 |
| St. Charles County | 283,883 | 343,207 | 349,407 | 23.1% | 65,524 | 1.8% | 6,200 |
| St. Clair County | 9,652 | 9,396 | 9,270 | -4.0% | -382 | -1.3% | -126 |
| Ste. Genevieve County | 17,842 | 17,822 | 17,720 | -0.7% | -122 | -0.6% | -102 |
| St. Francois County | 55,641 | 62,762 | 63,214 | 13.6% | 7,573 | 0.7% | 452 |
| St. Louis County | 1,016,315 | 993,512 | 991,830 | -2.4% | -24,485 | -0.2% | -1,682 |
| Saline County | 23,756 | 22,614 | 22,505 | -5.3% | -1,251 | -0.5% | -109 |
| Schuyler County | 4,170 | 4,088 | 4,110 | -1.4% | -60 | 0.5% | 22 |
| Scotland County | 4,983 | 4,802 | 4,798 | -3.7% | -185 | -0.1% | -4 |
| Scott County | 40,422 | 40,705 | 40,673 | 0.6% | 251 | -0.1% | -32 |
| Shannon County | 8,324 | 8,404 | 8,423 | 1.2% | 99 | 0.2% | 19 |
| Shelby County | 6,799 | 6,492 | 6,411 | -5.7% | -388 | -1.2% | -81 |
| Stoddard County | 29,705 | 29,687 | 29,537 | -0.6% | -168 | -0.5% | -150 |
| Stone County | 28,658 | 31,491 | 31,551 | 10.1% | 2,893 | 0.2% | 60 |
| Sullivan County | 7,219 | 6,657 | 6,629 | -8.2% | -590 | -0.4% | -28 |
| Taney County | 39,703 | 45,677 | 47,023 | 18.4% | 7,320 | 2.9% | 1,346 |
| Texas County | 23,003 | 24,557 | 24,598 | 6.9% | 1,595 | 0.2% | 41 |
| Vernon County | 20,454 | 19,988 | 20,009 | -2.2% | -445 | 0.1% | 21 |
| Warren County | 24,525 | 30,414 | 31,214 | 27.3% | 6,689 | 2.6% | 800 |
| Washington County | 23,344 | 24,282 | 24,548 | 5.2% | 1,204 | 1.1% | 266 |
| Wayne County | 13,259 | 12,639 | 12,652 | -4.6% | -607 | 0.1% | 13 |
| Webster County | 31,045 | 35,883 | 36,473 | 17.5% | 5,428 | 1.6% | 590 |
| Worth County | 2,382 | 2,093 | 2,039 | -14.4% | -343 | -2.6% | -54 |
| Wright County | 17,955 | 18,256 | 18,443 | 2.7% | 488 | 1.0% | 187 |
| St. Louis city | 348,189 | 355,663 | 354,361 | 1.8% | 6,172 | -0.4% | -1,302 |
